Regenerative Medicine, US Technology

Although still considered experimental by the FDA, stem-cell therapy shows impressive outcomes in treating a wide range of conditions, including orthopedic, neurologic, autoimmune, GI, cardiovascular, kidney/liver issues and more. Leading the charge when it comes to advanced stem cell and exosome therapies, R3 Stem Cell operates 70 locations in seven countries, and it is the company’s mission to provide customised, high-quality, affordable treatments to help patients achieve a better quality of life. This has netted its team the well-deserved title of Leading Innovators in Regenerative Cell Therapy 2025 – USA, and we take a deep dive into this innovation below.

For more than a decade, R3 Stem Cell has been providing patients from all over the world with regenerative stem cell and exosome therapies, treatments designed to harness the natural healing powers of the body and provide patients with hope. This hope often turns out to be transformative in the lives of individuals dealing with the likes of tissue injuries and chronic pain, and these groups are soon able to do things many of us take for granted – such as hiking, biking, or swimming – without any of their previous discomfort.

The health market is flooded with a number of pain-management therapies, mostly doing a good short term job of relieving symptoms but not actually fixing the root cause of the pain. R3 Stem Cell is much more than simply pain management, and the company has an established track record of long term results for pain relief, which allows patients to avoid surgery as a result of the treatments.

As an example of its distinction in this field, R3 Stem Cell was the first company in the US to achieve approval from an Institutional Review Board for the investigation of regenerative therapies with amniotic and umbilical cord tissue for a number of condition categories. More information about this study is available here, but it essentially corroborates the company’s claim of being an undisputed leader, both in its home of the US and beyond.

R3 Stem Cell currently offers its procedures in seven countries – the US, Mexico, the Philippines, South Africa, Pakistan, India, and Turkey. These regenerative treatments cover everything from stem cells to exosomes and platelet-rich plasma (PRP) to vitamins and peptides, and they are all fully customised to ensure patients are afforded the best results. Exploring this further, R3 Stem Cell’s therapies are inclusive of more than 25 customised protocols, all of which are catered to the specific ailment(s) of each patient.

Across its unrivalled range of regenerative therapies, R3 Stem Cell’s tissue products come from FDA registered, cGMP-compliant, and ISO-certified labs. According to R3 CEO David Greene, MD, PhD, MBA, “We never sacrifice quality control testing when producing the stem cell and exosome products for patients. My family and I receive procedures frequently with our stem cells, and our patients deserve to be treated like family!”

Behind every procedure in every location – the company deems its 70 sites ‘Centers of Excellence’ – there is a team of experienced, compassionate providers, individuals committed to delivering safe and effective care to their patients at every turn. To date, more than 26,000 of these procedures have been carried out, resulting in an 85% patient satisfaction rate. For something still considered experimental, this is highly impressive.

When it is not setting the gold standard for regenerative therapies through its cutting-edge stem cell procedures, R3 Stem Cell can be found educating consumers on the dangers of cheap stem-cell therapies, which are becoming increasingly popular in this space. These providers will often refuse to show patients an analysis certificate from the tissue lab – a big red flag. Most of the time, the tissue is inauthentic and not of the advertised quality. Similarly, some clinics even promote PRP as a stem-cell procedure.

By refusing to sacrifice on the quality it has become famous for, R3 Stem Cell boasts a number of success stories from patients satisfied with the treatments they received. There are some huge names within this portfolio, including Arnel Pineda, the current lead singer of the legendary rock band Journey; Ryan Paevey, an actor and model famous for his role in General Hospital; and Otis Wilson, a former Super Bowl champion.

On the back of this acclaim and these celebrity endorsements, R3 Stem Cell is continuing to move the needle in the field of regenerative therapy, a feat reflected through the title bestowed upon its team in this feature. For more information about any of the therapies discussed above, follow the link below to the company website.  

Contact Details

Contact: David Greene, MD, PhD, MBA

Company: R3 Stem Cell

Web Address: https://r3stemcell.com/